Description

Quinoline, 6-Isothiocyanato- is a specialized heterocyclic building block featuring a reactive isothiocyanate group at the 6-position of the quinoline core. This compound is of significant value in synthetic organic chemistry for the construction of more complex molecular architectures, particularly in pharmaceutical and agrochemical research. It serves as a critical intermediate for researchers and manufacturers developing active ingredients, dyes, and advanced materials who require high-purity, reliable starting materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting various disease pathways.
• Agrochemical Synthesis: Used in the research and development of new pesticides, herbicides, and fungicides, leveraging its reactive site for derivatization.
• Dye and Pigment Manufacturing: Serves as a precursor for the production of specialized quinoline-based dyes and colorants.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for metal complexes used in catalytic processes.
• Material Science Research: Utilized in the synthesis of organic semiconductors, fluorescent markers, and other advanced functional materials.
• Bioconjugation Chemistry: The isothiocyanate group allows for covalent attachment to amines, making it useful for labeling proteins and other biomolecules in research settings.

Basic Information

Product Name	Quinoline, 6-Isothiocyanato-
CAS No.	88240-51-1
Molecular Formula	C₁₀H₆N₂S
Molecular Weight	186.23 g/mol
Synonyms	6-Isothiocyanatoquinoline; 6-Quinolinyl isothiocyanate; Isothiocyanic acid, 6-quinolyl ester; 6-QITC; Quinoline-6-isothiocyanate; 6-Quinolyl isothiocyanate; 6-NCS-Quinoline; 1,3-Benzodiazole-6-isothiocyanate (related structural analog)
EINECS	Contact for details

Quality Control

Our Quinoline, 6-Isothiocyanato- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment, NMR and IR for structural confirmation, and tests for residual solvents and moisture. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.