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3β-[[6-o-(6-o-β-D-Glucopyranosyl-β-D-Glucopyranosyl)-β-D-Glucopyranosyl]Oxy]-14-Hydroxy-5α-Card-20(22)-Enolide CAS NO 88235-61-4
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CAS No.:88235-61-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
3β-[[6-o-(6-o-β-D-Glucopyranosyl-β-D-Glucopyranosyl)-β-D-Glucopyranosyl]Oxy]-14-Hydroxy-5α-Card-20(22)-Enolide is a high-purity, complex cardiac glycoside derivative, specifically a digoxin-related compound. This specialized chemical is critical for pharmaceutical research and development, particularly in the study of cardiac pharmacology and the synthesis of novel therapeutic agents. It is primarily sought by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on cardiovascular drug discovery and advanced chemical synthesis.
Application
- Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method development in drug manufacturing.
- Cardiac Drug Research: Used as a key intermediate or active pharmaceutical ingredient (API) precursor in the research and development of novel cardiotonic agents.
- Biochemical Studies: Employed in pharmacological assays to study the mechanism of action of Na+/K+-ATPase inhibition and its effects on myocardial contractility.
- Academic Research: Utilized in university and institutional labs for studies in medicinal chemistry, natural product chemistry, and structural biology.
- Process Development: Acts as a critical intermediate for process chemists developing scalable synthetic routes for complex glycosides.
- Metabolite Identification: Used in ADME (Absorption, Distribution, Metabolism, and Excretion) studies to identify and characterize drug metabolites.
Basic Information
| Product Name | 3β-[[6-o-(6-o-β-D-Glucopyranosyl-β-D-Glucopyranosyl)-β-D-Glucopyranosyl]Oxy]-14-Hydroxy-5α-Card-20(22)-Enolide |
| CAS No. | 88235-61-4 |
| Molecular Formula | C47H74O20 |
| Molecular Weight | 959.08 g/mol |
| Synonyms | Lanadoxin; 3β-[(O-6-Deoxy-α-L-mannopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-14-hydroxy-5β-card-20(22)-enolide (related isomer); Digoxin triglycoside analog; Cardiac glycoside trisaccharide; 14-Hydroxy-3β-[(tri-O-β-D-glucopyranosyl)oxy]-5α-card-20(22)-enolide; Strophanthus glycoside derivative |
| EINECS | Contact for details |
Quality Control
Our 3β-[[6-o-(6-o-β-D-Glucopyranosyl-β-D-Glucopyranosyl)-β-D-Glucopyranosyl]Oxy]-14-Hydroxy-5α-Card-20(22)-Enolide is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the exacting standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storage under an inert atmosphere.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Retention time matches reference standard |
| Purity (HPLC) | ≥ 98.0% |
| Water Content (KF) | ≤ 2.0% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | ≤ 10 ppm |
| Residual Solvents (GC) | Complies with ICH Q3C guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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