Description

3-Pyridinecarboxylic Acid, 4-(Chlorocarbonyl)-, Methyl Ester (9Ci) is a versatile pyridine derivative and a key reactive intermediate in organic synthesis. Its molecular structure, featuring both an ester and an acid chloride functional group, makes it a valuable building block for constructing more complex heterocyclic and pharmaceutical compounds. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality raw materials for advanced synthesis.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system or with nicotinic receptor activity.
• Agrochemical Synthesis: Used in the development of novel herbicides, insecticides, and fungicides, leveraging the pyridine core for biological activity.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing complex ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the creation of advanced polymers and functional materials with specific electronic or binding properties.
• Chemical Research & Development: A fundamental building block in academic and industrial R&D for exploring new chemical entities and reaction pathways.

Basic Information

Product Name	3-Pyridinecarboxylic Acid, 4-(Chlorocarbonyl)-, Methyl Ester (9Ci)
CAS No.	88234-88-2
Molecular Formula	C8H6ClNO3
Molecular Weight	199.59 g/mol
Synonyms	4-(Chlorocarbonyl)nicotinic acid methyl ester; Methyl 4-(chlorocarbonyl)nicotinate; Methyl 4-(chloroformyl)pyridine-3-carboxylate; 3-Pyridinecarboxylic acid, 4-(chlorocarbonyl)-, methyl ester; 4-(Methoxycarbonyl)nicotinoyl chloride; Nicotinic acid, 4-(chlorocarbonyl)-, methyl ester
EINECS	Contact for details

Quality Control

Our production of 3-Pyridinecarboxylic Acid, 4-(Chlorocarbonyl)-, Methyl Ester (9Ci) adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, guaranteeing traceability and compliance with your research or manufacturing specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.