Description

2-Furancarbonyl Chloride, Tetrahydro-4-Methyl-5-Oxo-, (2S-Cis)- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its value lies in its reactive acid chloride functionality and the defined stereocenter, enabling the precise construction of complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in constructing lactone or heterocyclic cores.
• Agrochemical Synthesis: Used in creating advanced, stereospecific active ingredients for crop protection products.
• Asymmetric Catalysis Research: Serves as a substrate or ligand precursor in the development of new chiral catalysts.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring high stereochemical purity.
• Academic & Institutional Research: Utilized in universities and research institutes for methodological studies in synthetic organic chemistry.
• Peptide Mimetic Chemistry: The reactive carbonyl chloride group facilitates the introduction of the furanone moiety into peptide-like structures for bioactivity studies.

Basic Information

Product Name	2-Furancarbonyl Chloride, Tetrahydro-4-Methyl-5-Oxo-, (2S-Cis)- (9Ci)
CAS No.	88218-43-3
Molecular Formula	C7H7ClO3
Molecular Weight	174.58 g/mol
Synonyms	(4S)-4-Methyl-5-oxotetrahydrofuran-2-carbonyl chloride; (2S,4S)-4-Methyl-5-oxo-2-tetrahydrofurancarbonyl chloride; (S)-4-Methyl-5-oxotetrahydrofuran-2-carboxylic acid chloride; (2S-cis)-Tetrahydro-4-methyl-5-oxo-2-furancarbonyl chloride; L-4-Methyl-5-oxo-2-tetrahydrofurancarbonyl chloride; (S)-Pantolactone acid chloride; (S)-Pantoyl chloride; 2-Furoyl chloride, tetrahydro-4-methyl-5-oxo-, (2S-cis)-
EINECS	Contact for details

Quality Control

Our 2-Furancarbonyl Chloride, Tetrahydro-4-Methyl-5-Oxo-, (2S-Cis)- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic and highly volatile nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from moisture, strong bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.