Description

2-Furancarbonyl Chloride, Tetrahydro-4-Methyl-5-Oxo-, (2S-Trans)- (9Ci) is a chiral, high-purity chemical intermediate characterized by its specific stereochemistry and reactive carbonyl chloride functional group. This compound matters for its role as a critical building block in the synthesis of complex, optically active molecules, enabling precise control over the final product's biological and chemical properties. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing advanced active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) and cardiovascular drugs.
• Agrochemical Synthesis: Used in the production of advanced, stereospecific pesticides and herbicides where the specific spatial orientation of the molecule is crucial for efficacy.
• Fine Chemical Production: Serves as a versatile precursor in the manufacture of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Academic & Industrial Research: Employed in chemical research for method development and the exploration of new asymmetric synthesis pathways.
• Material Science: Potential application as a monomer or modifying agent for creating polymers with specific chiral properties.

Basic Information

Product Name	2-Furancarbonyl Chloride, Tetrahydro-4-Methyl-5-Oxo-, (2S-Trans)- (9Ci)
CAS No.	88218-40-0
Molecular Formula	C7H9ClO3
Molecular Weight	176.60 g/mol
Synonyms	(2S-trans)-Tetrahydro-4-methyl-5-oxo-2-furancarbonyl chloride; (2S,4S)-4-Methyl-5-oxotetrahydrofuran-2-carbonyl chloride; 4-Methyl-5-oxotetrahydro-2-furoyl chloride, (2S-trans)-; 5-Oxo-4-methyltetrahydro-2-furoyl chloride; L-4-Methyl-5-oxotetrahydro-2-furoyl chloride; (2S,4S)-4-Methyl-5-oxodihydro-2-furancarbonyl chloride; Tetrahydro-4-methyl-5-oxo-2-furoyl chloride
EINECS	Contact for details

Quality Control

Our 2-Furancarbonyl Chloride, Tetrahydro-4-Methyl-5-Oxo-, (2S-Trans)- (9Ci) is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.