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5,14-Dihydroxy-3β-[(D-Glucopyranosyl)Oxy]-19-Oxo-5β-Card-20(22)-Enolide CAS NO 88195-74-8


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CAS No.:88195-74-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

5,14-Dihydroxy-3β-[(D-Glucopyranosyl)Oxy]-19-Oxo-5β-Card-20(22)-Enolide is a specialized cardiac glycoside derivative, a class of compounds known for their significant biological activity. This high-purity intermediate is critical for pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents targeting cardiovascular conditions. It serves as a key building block for researchers and manufacturers in the pharmaceutical and biotechnology sectors seeking to develop new drug candidates or reference standards.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of novel cardiac glycoside-based drug candidates and active pharmaceutical ingredients (APIs).
  • Biochemical Research: Used as a reference standard or probe compound in studies investigating sodium-potassium ATPase (Na⁺/K⁺-ATPase) inhibition and cardiac cell signaling pathways.
  • Analytical Standard: Serves as a high-purity certified reference material (CRM) for quality control and method validation in analytical laboratories (HPLC, LC-MS).
  • Preclinical Development: Employed in the early-stage development and screening of potential cardioprotective or inotropic agents.

Basic Information

Item Details
Product Name 5,14-Dihydroxy-3β-[(D-Glucopyranosyl)Oxy]-19-Oxo-5β-Card-20(22)-Enolide
CAS No. 88195-74-8
Molecular Formula C₂₉H₄₂O₁₂
Molecular Weight 582.64 g/mol
Synonyms 19-Oxocymarin; 3β-(β-D-Glucopyranosyloxy)-5,14-dihydroxy-19-oxo-5β-card-20(22)-enolide; Cymarin 19-oxo derivative; 19-Ketocymarin; 5,14-Dihydroxy-3β-(β-D-glucopyranosyloxy)-19-oxo-5β,20(22)-cardenolide; Cardiac glycoside derivative (88195-74-8); 19-Oxo cymarin
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Quality Control

Our 5,14-Dihydroxy-3β-[(D-Glucopyranosyl)Oxy]-19-Oxo-5β-Card-20(22)-Enolide is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 2.0%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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