Description

Azidoalanine is a specialized non-proteinogenic amino acid derivative featuring a reactive azido functional group. This compound is a crucial building block in chemical biology and pharmaceutical research, enabling the synthesis of complex molecules through bioorthogonal click chemistry. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and agrochemical sectors for applications ranging from drug discovery to materials science.

Application

• Peptide Synthesis & Modification: Key intermediate for incorporating azide handles into peptides and proteins for subsequent conjugation via click chemistry (e.g., CuAAC, SPAAC).
• Chemical Biology Probes: Used to create activity-based probes and affinity tags for studying enzyme function, protein-protein interactions, and cellular localization.
• Bioconjugation & ADC Development: Enables site-specific labeling of antibodies, proteins, and other biomolecules for the development of antibody-drug conjugates (ADCs) and diagnostic agents.
• Materials Science: Serves as a monomer or cross-linker for synthesizing functional polymers and hydrogels with tailored biological properties.
• Agrochemical Research: Intermediate in the synthesis of novel bioactive compounds with potential herbicidal or pesticidal activity.
• Glycobiology: Building block for synthesizing azido-labeled sugars and glycoconjugates for metabolic labeling and imaging studies.

Basic Information

Product Name	Azidoalanine
CAS No.	88192-18-1
Molecular Formula	C3H6N4O2
Molecular Weight	130.10 g/mol
Synonyms	2-Azido-3-aminopropanoic acid; 3-Amino-2-azidopropanoic acid; (R/S)-2-Azidoalanine; DL-2-Azidoalanine; Azido-Ala; AzAla; 2-Azidoalanine; β-Azidoalanine
EINECS	Contact for details

Quality Control

Our Azidoalanine is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation and degradation. Keep away from heat, sparks, and open flames. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.