Description

2-[(2-Azidoethoxy)Methyl]-4-(2-Chlorophenyl)-3-Ethoxycarbonyl-5-Methoxycarbonyl)-6-Methyl-1,4-Dihydropyridine is a specialized dihydropyridine derivative, a class of compounds renowned for their significant biological and chemical activity. This compound is a critical advanced pharmaceutical intermediate (API intermediate) used in the synthesis of complex active ingredients. It is primarily required by pharmaceutical R&D and fine chemical synthesis sectors for developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel calcium channel blockers and other bioactive dihydropyridine-based drugs.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for cardiovascular and neurological targets.
• Chemical Biology Probes: The azido functional group allows for bioorthogonal "click chemistry" applications, enabling labeling and tracking of biomolecules.
• Fine Chemical Synthesis: Serves as a precursor for synthesizing complex heterocyclic compounds with potential agrochemical or material science applications.
• Academic & Industrial R&D: A valuable reagent for universities and contract research organizations (CROs) exploring new chemical entities.

Basic Information

Product Name	2-[(2-Azidoethoxy)Methyl]-4-(2-Chlorophenyl)-3-Ethoxycarbonyl-5-Methoxycarbonyl)-6-Methyl-1,4-Dihydropyridine
CAS No.	88150-46-3
Molecular Formula	C21H25ClN4O6
Molecular Weight	464.90 g/mol
Synonyms	1,4-Dihydro-2-[(2-azidoethoxy)methyl]-4-(2-chlorophenyl)-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester; 3-Ethyl 5-methyl 2-[(2-azidoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-3,5-pyridinedicarboxylate; Azido-functionalized DHP derivative; 2-Chlorophenyl DHP azido ether; CAS 88150-46-3; 1,4-DHP intermediate with azido linker; Click chemistry dihydropyridine reagent.
EINECS	Contact for details

Quality Control

Our high-purity pharmaceutical intermediate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and Mass Spectrometry. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your internal specifications and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). For long-term storage, consider packaging under an inert gas such as nitrogen or argon in a sealed container. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.