Description

5'-Bromoacetamido-5'-Deoxyadenosine is a high-purity, functionalized nucleoside derivative designed for advanced bioconjugation and cross-linking applications. This compound is a critical reagent for researchers and manufacturers developing targeted therapeutics, diagnostic probes, and novel biomaterials. It is primarily utilized in pharmaceutical R&D, life sciences, and biotechnology for the site-specific modification of oligonucleotides, proteins, and other biomolecules.

Application

• Bioconjugation Reagent: Used for the covalent attachment of labels, drugs, or other functional groups to oligonucleotides and proteins.
• Cross-linking Agent: Employed in the study of biomolecular interactions and the construction of stable molecular complexes.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel nucleoside-based prodrugs and targeted cancer therapies.
• Diagnostic Probe Development: Essential for creating labeled probes for fluorescence in situ hybridization (FISH) and other detection assays.
• Affinity Labeling: Utilized to identify and characterize active sites of enzymes and receptors.
• Material Science: Applied in the surface functionalization of nanoparticles and other substrates for biosensor development.

Basic Information

Product Name	5'-Bromoacetamido-5'-Deoxyadenosine
CAS No.	87932-45-4
Molecular Formula	C₁₂H₁₄BrN₇O₄
Molecular Weight	400.19 g/mol
Synonyms	5'-(Bromoacetamido)-5'-deoxyadenosine; N-[2-(6-Amino-9H-purin-9-yl)ethyl]-2-bromoacetamide; 5'-Deoxy-5'-(bromoacetamido)adenosine; 5'-Bromoacetamidoadenosine; 9H-Purin-6-amine, N-[2-(6-amino-9H-purin-9-yl)ethyl]-2-bromoacetamide; BAD; Br-Ac-5'-dA
EINECS	Contact for details

Quality Control

Our 5'-Bromoacetamido-5'-Deoxyadenosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent controls for residual solvents and moisture. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.