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5-Fluoro-2'-Deoxyuridine Diphosphate-n-Acetylglucosamine CAS NO 87810-49-9


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CAS No.:87810-49-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

5-Fluoro-2'-Deoxyuridine Diphosphate-n-Acetylglucosamine is a specialized nucleotide sugar derivative, a key biochemical intermediate in glycosylation research and development. This compound is critical for studying and modulating enzymatic pathways involved in nucleotide sugar metabolism and glycoconjugate synthesis. It is primarily utilized by researchers and manufacturers in the fields of pharmaceutical development, biochemical research, and enzymology, where precise control over glycosylation processes is essential.

Application

  • Biochemical Research: As a substrate for studying glycosyltransferase and other carbohydrate-processing enzymes.
  • Drug Discovery: Used in the development of novel antiviral and anticancer agents that target nucleotide metabolism pathways.
  • Enzymology Studies: Serves as a critical reagent for investigating enzyme kinetics and inhibition mechanisms.
  • Glycobiology: A key intermediate for the in vitro synthesis of complex oligosaccharides and glycoconjugates.
  • Metabolic Pathway Analysis: Employed in tracer studies to elucidate cellular metabolic fluxes related to nucleotide sugars.
  • Pharmaceutical Intermediates: Potential use as a building block for the synthesis of more complex nucleoside-based active pharmaceutical ingredients (APIs).

Basic Information

Item Details
Product Name 5-Fluoro-2'-Deoxyuridine Diphosphate-n-Acetylglucosamine
CAS No. 87810-49-9
Molecular Formula C17H25FN3O16P2
Molecular Weight 608.33 g/mol
Synonyms 5-Fluoro-2'-deoxyuridine diphosphate N-acetylglucosamine; 5-FdUDP-GlcNAc; FdUDP-GlcNAc; 5-Fluoro-2'-deoxyuridine 5'-(trihydrogen diphosphate) P'→5'-ester with 2-(acetylamino)-2-deoxy-D-glucopyranose; UDP-5-Fluoro-2'-deoxyuridine N-acetylglucosamine (incorrect but common alias); Nucleotide-sugar derivative of 5-fluoro-2'-deoxyuridine
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Quality Control

Our 5-Fluoro-2'-Deoxyuridine Diphosphate-n-Acetylglucosamine is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry, to ensure identity, potency, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your research and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. Due to its hygroscopic (moisture-sensitive) nature, the container should be sealed under an inert atmosphere (e.g., argon or nitrogen) after each use and allowed to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item Specification
Appearance White to off-white powder or solid
Identification (HPLC) Conforms to reference standard
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95%
Water Content (KF) ≤ 3.0%
Solubility Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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