Description

1-(2-Deoxy-(2-Fluoroarabinofuranosyl))-5-Vinyluracil is a fluorinated nucleoside analog of significant interest in pharmaceutical research and development. This compound is a key intermediate in the synthesis of novel antiviral and anticancer agents, leveraging its modified sugar and base moieties to target specific enzymatic pathways. It is primarily sought by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the development of nucleoside-based therapeutics. The product is supplied with a focus on high purity and batch-to-batch consistency to support critical R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of experimental antiviral drugs, particularly those targeting viral polymerases.
• Anticancer Agent Research: Used in preclinical studies to develop novel chemotherapeutic agents that inhibit cancer cell proliferation.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies to understand nucleoside metabolism and related biological mechanisms.
• Process Chemistry & Scale-Up: Utilized in process development and optimization for the commercial manufacturing of active pharmaceutical ingredients (APIs).
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.

Basic Information

Product Name	1-(2-Deoxy-(2-Fluoroarabinofuranosyl))-5-Vinyluracil
CAS No.	87782-49-8
Molecular Formula	C11H13FN2O5
Molecular Weight	272.23 g/mol
Synonyms	5-Vinyl-1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)uracil; 2'-Fluoro-2'-deoxy-5-vinyluridine; 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-vinyluracil; 5-Vinyl-1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)pyrimidine-2,4(1H,3H)-dione; 2'-F-5-Vinyl-ara-U; FV-araU; 87782-49-8; 5-Vinyl-2'-fluoro-2'-deoxyuridine
EINECS	Contact for details

Quality Control

Our 1-(2-Deoxy-(2-Fluoroarabinofuranosyl))-5-Vinyluracil is manufactured under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and conformity to specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support development needs with custom purity grades and can align with cGMP standards for advanced clinical stage materials upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%
Related Substances (HPLC)	Total impurities ≤3.0% Any single impurity ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.