Description

4-Piperidinecarbonyl Chloride, 4-Hydroxy-1-Methyl- (9Ci) is a versatile and reactive piperidine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its dual functionality, featuring both a reactive acid chloride group and a hydroxyl group, enabling its use in constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of piperidine-based drug candidates, including potential central nervous system (CNS) agents and receptor modulators.
• Agrochemical Research: Used in creating novel pesticides and herbicides where the piperidine scaffold contributes to biological activity.
• Chemical Synthesis: Employed in peptide coupling reactions and as a precursor for amides and esters due to its reactive carbonyl chloride group.
• Material Science: Potential monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Academic & R&D: Serves as a valuable reagent in medicinal chemistry research for library synthesis and structure-activity relationship (SAR) studies.

Basic Information

Product Name	4-Piperidinecarbonyl Chloride, 4-Hydroxy-1-Methyl- (9Ci)
CAS No.	87752-57-6
Molecular Formula	C7H12ClNO2
Molecular Weight	177.63 g/mol
Synonyms	1-Methyl-4-hydroxy-4-piperidinecarbonyl chloride; 4-Hydroxy-1-methylpiperidine-4-carboxylic acid chloride; 4-(Chlorocarbonyl)-4-hydroxy-1-methylpiperidine; 1-Methyl-4-piperidinol-4-carboxylic acid chloride; 4-Hydroxy-N-methyl-4-piperidinecarbonyl chloride; 4-Hydroxy-1-methylpiperidine-4-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 4-Piperidinecarbonyl Chloride, 4-Hydroxy-1-Methyl- (9Ci) is produced under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and scale-up. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of GMP environments for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and reacts with strong acids and organic solvents; ensure the container is kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.