Description

5-(2-Iodovinyl)-2'-Deoxyuridine is a halogenated nucleoside analog of significant interest in pharmaceutical research and development. This compound serves as a critical intermediate and a potent antiviral agent, particularly in the study of herpesviruses. It is primarily utilized by research institutions, pharmaceutical companies, and biotechnology firms engaged in antiviral drug discovery and biochemical studies. The product is supplied to meet the stringent purity requirements of advanced research and development applications.

Application

• Antiviral Research: Key intermediate and active compound in the development of novel antiviral therapies, especially against herpes simplex virus (HSV) and varicella-zoster virus (VZV).
• Biochemical Studies: Used as a substrate or inhibitor in enzymatic studies to understand nucleoside metabolism and DNA synthesis pathways.
• Radiopharmaceutical Precursor: Serves as a precursor molecule for the synthesis of radioiodinated compounds used in diagnostic imaging and targeted radiotherapy.
• Medicinal Chemistry: A valuable building block for the synthesis of more complex nucleoside analogs with enhanced pharmacological properties.
• Academic Research: Employed in university and institutional labs for fundamental virology and molecular biology research projects.

Basic Information

Product Name	5-(2-Iodovinyl)-2'-Deoxyuridine
CAS No.	87727-68-2
Molecular Formula	C11H13IN2O5
Molecular Weight	380.14 g/mol
Synonyms	IVDU; (E)-5-(2-Iodovinyl)-2'-deoxyuridine; 1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-[(E)-2-iodoethenyl]pyrimidine-2,4-dione; 5-(2-Iodoethenyl)-2'-deoxyuridine; NSC 718681; (E)-IVdU; 2'-Deoxy-5-(2-iodovinyl)uridine
EINECS	Contact for details

Quality Control

Our 5-(2-Iodovinyl)-2'-Deoxyuridine is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemical production, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.