Description

Etarotene is a synthetic retinoid compound with the CAS registry number 87719-32-2, recognized for its potent biological activity in modulating cell growth and differentiation. This high-purity intermediate is critical for pharmaceutical research and development, particularly in dermatology and oncology. It is primarily utilized by R&D laboratories and manufacturers in the pharmaceutical and biotechnology sectors for the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of advanced retinoid-based drugs for treating skin conditions and cancers.
• Biochemical Research: Used as a reference standard and active agent in studies of retinoid receptor pathways and gene expression.
• Dermatological Formulations: Serves as a precursor in developing topical and systemic treatments for acne, psoriasis, and photoaging.
• Oncology Research: Investigated for its potential in differentiation therapy and as a component in targeted cancer treatments.
• Cosmeceutical Development: Employed in R&D for high-performance anti-aging and skin-repair products.

Basic Information

Product Name	Etarotene
CAS No.	87719-32-2
Molecular Formula	C21H26O3
Molecular Weight	326.43 g/mol
Synonyms	Ethyl 4-[2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl]benzoate; Ro 13-7410; TTNN; Arotinoid Ethyl Ester; Ethyl Arotinoid
EINECS	Contact for details

Quality Control

Our Etarotene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets stringent specifications for pharmaceutical research. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.