Description

4-Pyridinecarbonyl Chloride, 2,6-Dimethyl- (9Ci) is a versatile and highly reactive acyl chloride derivative of a substituted pyridine, serving as a critical building block in advanced organic synthesis. Its core value lies in enabling the efficient introduction of the 2,6-dimethylisonicotinoyl moiety into target molecules, a key step in constructing complex pharmacophores and functional materials. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity intermediates for the development of active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the 2,6-dimethylpyridine scaffold imparts specific biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Polymer Modification: Employed to introduce functional pyridine groups into polymer chains, modifying material properties for specialty coatings or membranes.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new reaction pathways and creating novel heterocyclic compounds.
• Peptide Mimetics: Used in medicinal chemistry to create peptide analogs and conformationally restricted scaffolds.

Basic Information

Item	Details
Product Name	4-Pyridinecarbonyl Chloride, 2,6-Dimethyl- (9Ci)
CAS No.	87647-00-5
Molecular Formula	C8H8ClNO
Molecular Weight	169.61 g/mol
Synonyms	2,6-Dimethylisonicotinoyl chloride; 2,6-Dimethylpyridine-4-carbonyl chloride; 4-Carboxy-2,6-dimethylpyridine chloride; Isonicotinic acid, 2,6-dimethyl-, chloride; 2,6-Lutidine-4-carbonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 4-Pyridinecarbonyl Chloride, 2,6-Dimethyl- (9Ci) is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards through rigorous analytical controls, including HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and reactive acid chloride nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from strong bases, oxidizing agents, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.