Description

4-Azidobutyric Acid Methyl Ester is a versatile organic azide compound, primarily valued as a key click chemistry reagent for the synthesis of complex molecules. Its high reactivity, particularly in Huisgen 1,3-dipolar cycloaddition reactions, makes it an essential building block for creating triazole linkages under mild conditions. This product is critical for researchers and manufacturers in pharmaceutical development, materials science, and bioconjugation who require reliable, high-purity intermediates for advanced synthesis.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and prodrugs via click chemistry methodologies.
• Bioconjugation & Probe Synthesis: Serves as a linker for attaching fluorescent dyes, affinity tags, or other functional groups to biomolecules like proteins, peptides, and oligonucleotides.
• Polymer & Materials Science: Employed as a cross-linking agent or functional monomer to introduce azide groups into polymers, hydrogels, and surface coatings.
• Chemical Biology Research: A crucial tool for activity-based protein profiling (ABPP) and the development of chemical probes to study biological pathways.
• Agrochemical Synthesis: Acts as a building block in the research and development of novel crop protection agents.
• Diagnostic Reagent Manufacturing: Utilized in the production of components for diagnostic assays and imaging agents.

Basic Information

Product Name	4-Azidobutyric Acid Methyl Ester
CAS No.	87517-47-3
Molecular Formula	C5H9N3O2
Molecular Weight	143.14 g/mol
Synonyms	Methyl 4-azidobutanoate; 4-Azidobutanoic Acid Methyl Ester; Methyl γ-azidobutyrate; Azidobutyric Acid Methyl Ester; Butanoic acid, 4-azido-, methyl ester; γ-Azidobutyric Acid Methyl Ester; Methyl 4-azidobutyrate
EINECS	Contact for details

Quality Control

Our 4-Azidobutyric Acid Methyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at 2-8°C (refrigerated) or as specified on the label. Due to its highly volatile and reactive azide functional group, keep away from heat, sparks, and open flames. Isolate from strong reducing agents and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.