Description

Norchlorpromazine Isothiocyanate is a specialized organic compound belonging to the phenothiazine class, widely recognized as a key intermediate in advanced chemical synthesis. Its primary commercial value lies in its reactive isothiocyanate group, which facilitates the creation of novel derivatives for research and development. This compound is essential for pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents and diagnostic tools.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel phenothiazine-based drug candidates and active pharmaceutical ingredients (APIs).
• Bioconjugation Reagent: Used for labeling proteins, antibodies, and other biomolecules via its reactive isothiocyanate group for diagnostic and research applications.
• Chemical Research: Serves as a versatile precursor in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Dye and Pigment Synthesis: Employed in the development of specialized dyes and functional materials due to its phenothiazine core structure.
• Analytical Reference Standard: Used as a high-purity standard in analytical methods (HPLC, LC-MS) for quality control and regulatory testing.

Basic Information

Product Name	Norchlorpromazine Isothiocyanate
CAS No.	87508-98-3
Molecular Formula	C17H16ClN3S2
Molecular Weight	361.91 g/mol
Synonyms	10H-Phenothiazine-2-isothiocyanate, 10-(3-Chloropropyl)-; 2-Isothiocyanato-10-(3-chloropropyl)phenothiazine; Norchlorpromazine Isothiocyanate; Desmethylchlorpromazine Isothiocyanate; N-Desmethylchlorpromazine Isothiocyanate; Phenothiazine-2-isothiocyanate derivative; NSC 403169
EINECS	Contact for details

Quality Control

Our Norchlorpromazine Isothiocyanate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for research and pharmaceutical intermediate applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, impurity profile, and physical characteristics.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.