Description

1-(2-Chloro-6-Fluorophenyl)Ethan-1-Ol is a high-purity fluorinated aromatic alcohol building block of significant importance in advanced organic synthesis. Its unique structure, featuring both chloro and fluoro substituents on the phenyl ring, makes it a versatile chiral intermediate for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized chiral ligands used in asymmetric catalysis.
• Material Science Research: Employed in the development of specialty polymers and liquid crystals due to its aromatic and halogenated properties.
• Custom Synthesis & Contract Manufacturing: A critical building block for custom synthesis houses serving the life sciences sector.
• Academic & Industrial R&D: Used in methodological development and exploratory chemistry within university and corporate laboratories.

Basic Information

Product Name	1-(2-Chloro-6-Fluorophenyl)Ethan-1-Ol
CAS No.	87327-70-6
Molecular Formula	C8H8ClFO
Molecular Weight	174.60 g/mol
Synonyms	α-(2-Chloro-6-fluorophenyl)ethanol; 1-(2-Chloro-6-fluorophenyl)ethanol; (2-Chloro-6-fluorophenyl)methylcarbinol; 2-Chloro-6-fluoro-α-methylbenzyl alcohol; 2-Chloro-6-fluoro-α-phenethyl alcohol; 1-(2-Chloro-6-fluoro-phenyl)-ethanol; (RS)-1-(2-Chloro-6-fluorophenyl)ethan-1-ol
EINECS	Contact for details

Quality Control

Our 1-(2-Chloro-6-Fluorophenyl)Ethan-1-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and enantiomeric/exact isomeric consistency as required. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for scale-up and regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.