Description

N(6)-Methoxy-2',3',5'-Tri-o-Methyladenosine is a chemically modified nucleoside derivative, specifically an adenosine analog with selective methylation and methoxylation. This compound is valued for its role as a key synthetic intermediate and research tool in the development of novel pharmaceutical agents and biochemical probes. It is primarily utilized by research institutions and pharmaceutical companies engaged in nucleoside chemistry, antiviral drug discovery, and the study of enzyme mechanisms.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of modified nucleoside analogs for potential antiviral or anticancer therapeutics.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate adenosine-processing enzymes, such as methyltransferases and kinases.
• Probe Development: Acts as a precursor for labeled compounds (e.g., fluorescent or radioactive probes) used in cellular and molecular biology assays.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of nucleoside-based drug candidates.
• Reference Standard: Provides a high-purity standard for analytical method development and quality control in API (Active Pharmaceutical Ingredient) manufacturing.

Basic Information

Product Name	N(6)-Methoxy-2',3',5'-Tri-o-Methyladenosine
CAS No.	87079-99-0
Molecular Formula	C₁₇H₂₃N₅O₆
Molecular Weight	393.40 g/mol
Synonyms	6-Methoxy-2',3',5'-tri-O-methyladenosine; N6-Methoxy-2',3',5'-tri-O-methyladenosine; 6-Methoxy-2',3',5'-tri-O-methyl-9-β-D-ribofuranosyladenine; 2',3',5'-Tri-O-methyl-N6-methoxyadenosine; Adenosine, N6-methoxy-2',3',5'-tri-O-methyl-; N(6)-Methoxy-2',3',5'-tri-O-methyladenosine
EINECS	Contact for details

Quality Control

Our N(6)-Methoxy-2',3',5'-Tri-o-Methyladenosine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.