Description

Cyclohexanecarbonyl Chloride, 2-Methyl-5-(1-Methylethyl)-, [1S-(1Alpha,2Beta,5Alpha)]- (9Ci) is a high-purity, stereochemically defined chiral building block essential for advanced organic synthesis. Its value lies in its role as a key acylating agent and intermediate for introducing complex, terpene-derived structural motifs into target molecules. This compound is primarily needed by research and development laboratories, as well as production facilities in the pharmaceutical and agrochemical sectors for creating novel active ingredients with specific stereochemistry.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the synthesis of proprietary drug candidates, particularly in medicinal chemistry programs targeting complex natural product derivatives.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides where specific stereochemistry is crucial for biological activity.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in academic and industrial research focused on developing new chiral catalysts and synthetic methodologies.
• Fragrance and Flavor Chemistry: Acts as a building block for synthesizing high-value, stereochemically pure aroma chemicals and flavor compounds.
• Material Science Research: Utilized in the creation of specialized monomers or additives for polymers where the bulky, chiral structure can impart unique material properties.
• Custom Synthesis and Contract Manufacturing: A key starting material for fine chemical manufacturers offering bespoke synthesis services to clients in life sciences.

Basic Information

Item	Details
Product Name	Cyclohexanecarbonyl Chloride, 2-Methyl-5-(1-Methylethyl)-, [1S-(1Alpha,2Beta,5Alpha)]- (9Ci)
CAS No.	87001-70-5
Molecular Formula	C11H19ClO
Molecular Weight	202.72 g/mol
Synonyms	(1S,2R,5S)-2-Isopropyl-5-methylcyclohexanecarbonyl chloride; (-)-Menthyl chloroformate (specific isomer); L-Menthyl chloroformate; (1S,2R,5S)-Menthyl chloroformate; (1S)-1,2,5-Trimethyl-4-(1-methylethyl)cyclohexanecarbonyl chloride; [1S-(1α,2β,5α)]-2-Methyl-5-(1-methylethyl)cyclohexanecarbonyl chloride; Chiral Menthyl Carbonyl Chloride; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our Cyclohexanecarbonyl Chloride, 2-Methyl-5-(1-Methylethyl)-, [1S-(1Alpha,2Beta,5Alpha)]- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC and GC, to ensure high enantiomeric excess (e.e.) and chemical purity. Certificates of Analysis (COA) with detailed specifications are provided to guarantee consistency and traceability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic and highly volatile nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.