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n-(4-Azidosalicyl)-6-Amido-6-Deoxy-Glucopyranose CAS NO 86979-66-0
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CAS No.:86979-66-0
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
n-(4-Azidosalicyl)-6-Amido-6-Deoxy-Glucopyranose is a specialized biochemical reagent featuring a photoactivatable aryl azide group and a carbohydrate moiety. This compound is engineered for covalent crosslinking and labeling applications, enabling the study of carbohydrate-protein interactions and biomolecular assembly. It is primarily utilized by researchers and manufacturers in the fields of glycobiology, bioconjugation, and pharmaceutical development for creating stable, light-induced linkages in complex biological systems.
Application
- Photoaffinity Labeling: Used as a crosslinker to capture transient or weak interactions between glycans and their binding proteins (lectins, antibodies, enzymes) for identification and characterization.
- Bioconjugation & Probe Synthesis: Serves as a key intermediate for synthesizing fluorescent, affinity, or radioactive probes targeting carbohydrate-recognizing domains.
- Surface Immobilization: Facilitates the covalent attachment of carbohydrates or glycomimetics onto biosensor chips, microarray slides, or nanoparticle surfaces for interaction studies.
- Material Science & Hydrogel Formation: Employed in the development of smart biomaterials and hydrogels where light-triggered crosslinking enables precise spatial and temporal control over matrix properties.
- Drug Delivery System Development: Investigated for creating targeted delivery carriers where the ligand can be photo-crosslinked to the carrier system for enhanced stability.
Basic Information
| Product Name | n-(4-Azidosalicyl)-6-Amido-6-Deoxy-Glucopyranose |
| CAS No. | 86979-66-0 |
| Molecular Formula | C19H19N5O8 |
| Molecular Weight | 445.39 g/mol |
| Synonyms | 4-Azidosalicylamido-6-deoxyglucopyranose; ASG; 6-Deoxy-6-[(4-azido-2-hydroxybenzoyl)amino]-D-glucopyranose; N-(4-Azido-2-hydroxybenzoyl)-6-amino-6-deoxy-D-glucopyranose; 6-Amino-6-deoxy-D-glucose 4-azidosalicylamide; Photoactivatable glucopyranose derivative; Aryl azide glycoside |
| EINECS | Contact for details |
Quality Control
Our n-(4-Azidosalicyl)-6-Amido-6-Deoxy-Glucopyranose is produced and handled under strict quality protocols to ensure batch-to-batch consistency and reliability for sensitive research applications. Each lot undergoes comprehensive analytical characterization. A detailed Certificate of Analysis (COA) is provided, confirming identity, purity, and suitability for bioconjugation.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This compound is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture condensation. For long-term storage, keep under an inert atmosphere.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Conforms to reference |
| Purity (HPLC) | ≥ 95.0% |
| Water Content (KF) | ≤ 2.0% |
| Solubility | Soluble in DMSO, DMF; sparingly soluble in water |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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