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n-(4-Azidosalicyl)-6-Amido-6-Deoxy-Glucopyranose CAS NO 86979-66-0


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CAS No.:86979-66-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

n-(4-Azidosalicyl)-6-Amido-6-Deoxy-Glucopyranose is a specialized biochemical reagent featuring a photoactivatable aryl azide group and a carbohydrate moiety. This compound is engineered for covalent crosslinking and labeling applications, enabling the study of carbohydrate-protein interactions and biomolecular assembly. It is primarily utilized by researchers and manufacturers in the fields of glycobiology, bioconjugation, and pharmaceutical development for creating stable, light-induced linkages in complex biological systems.

Application

  • Photoaffinity Labeling: Used as a crosslinker to capture transient or weak interactions between glycans and their binding proteins (lectins, antibodies, enzymes) for identification and characterization.
  • Bioconjugation & Probe Synthesis: Serves as a key intermediate for synthesizing fluorescent, affinity, or radioactive probes targeting carbohydrate-recognizing domains.
  • Surface Immobilization: Facilitates the covalent attachment of carbohydrates or glycomimetics onto biosensor chips, microarray slides, or nanoparticle surfaces for interaction studies.
  • Material Science & Hydrogel Formation: Employed in the development of smart biomaterials and hydrogels where light-triggered crosslinking enables precise spatial and temporal control over matrix properties.
  • Drug Delivery System Development: Investigated for creating targeted delivery carriers where the ligand can be photo-crosslinked to the carrier system for enhanced stability.

Basic Information

Product Name n-(4-Azidosalicyl)-6-Amido-6-Deoxy-Glucopyranose
CAS No. 86979-66-0
Molecular Formula C19H19N5O8
Molecular Weight 445.39 g/mol
Synonyms 4-Azidosalicylamido-6-deoxyglucopyranose; ASG; 6-Deoxy-6-[(4-azido-2-hydroxybenzoyl)amino]-D-glucopyranose; N-(4-Azido-2-hydroxybenzoyl)-6-amino-6-deoxy-D-glucopyranose; 6-Amino-6-deoxy-D-glucose 4-azidosalicylamide; Photoactivatable glucopyranose derivative; Aryl azide glycoside
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Quality Control

Our n-(4-Azidosalicyl)-6-Amido-6-Deoxy-Glucopyranose is produced and handled under strict quality protocols to ensure batch-to-batch consistency and reliability for sensitive research applications. Each lot undergoes comprehensive analytical characterization. A detailed Certificate of Analysis (COA) is provided, confirming identity, purity, and suitability for bioconjugation.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This compound is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture condensation. For long-term storage, keep under an inert atmosphere.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Identification (HPLC) Conforms to reference
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 2.0%
Solubility Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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