Description

Diethyl (4-Chlorobutyl)Phosphonate is a versatile organophosphorus compound that serves as a critical intermediate in advanced organic synthesis. Its value lies in its bifunctional reactivity, featuring both a phosphonate ester group and a terminal chloroalkyl chain, enabling its use in the construction of complex molecular architectures. This chemical is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require a reliable building block for the synthesis of active pharmaceutical ingredients (APIs), ligands, and novel functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of bisphosphonate drugs and other therapeutic agents targeting bone metabolism.
• Agrochemical Synthesis: Used in the production of novel herbicides and plant growth regulators that incorporate phosphonate functionalities.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing phosphonate-based ligands used in coordination chemistry and homogeneous catalysis.
• Material Science: Employed in the development of flame retardants, plasticizers, and surface-modifying agents for polymers.
• Organic Synthesis Building Block: Utilized in Horner-Wadsworth-Emmons (HWE) olefination reactions and other carbon-carbon bond-forming processes.
• Research & Development: A valuable reagent for medicinal chemistry and chemical biology research in academic and industrial R&D laboratories.

Basic Information

Product Name	Diethyl (4-Chlorobutyl)Phosphonate
CAS No.	86791-04-0
Molecular Formula	C8H18ClO3P
Molecular Weight	228.65 g/mol
Synonyms	Diethyl 4-Chlorobutylphosphonate; (4-Chlorobutyl)phosphonic Acid Diethyl Ester; 4-Chlorobutylphosphonic Acid Diethyl Ester; Diethyl (4-Chlorobutyl)Phosphonate; Diethyl 4-Chlorobutylphosphonate; Phosphonic Acid, (4-Chlorobutyl)-, Diethyl Ester; Butylphosphonic Acid, 4-Chloro-, Diethyl Ester
EINECS	Contact for details

Quality Control

Our Diethyl (4-Chlorobutyl)Phosphonate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Density (20°C)	~1.15 g/cm³
Refractive Index (n20D)	~1.455

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.