Description

1-Piperidinecarbonyl Chloride, 2-Oxo- (9Ci) is a highly reactive acid chloride derivative of piperidine, serving as a critical building block in advanced organic synthesis. Its core value lies in enabling the efficient introduction of the 2-oxopiperidine-1-carbonyl moiety, a key structural motif in medicinal chemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of piperidine-based drug candidates, including kinase inhibitors, protease inhibitors, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in constructing complex molecules for crop protection agents, such as herbicides and fungicides with specific mode-of-action profiles.
• Chemical Biology & Proteomics: Employed as a reactive handle for labeling or modifying biomolecules to study protein function and interactions.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers with tailored thermal or mechanical properties.
• Custom Synthesis & Contract Manufacturing: Serves as a starting material for the production of bespoke fine chemicals and advanced intermediates under cGMP or research-grade conditions.

Basic Information

Product Name	1-Piperidinecarbonyl Chloride, 2-Oxo- (9Ci)
CAS No.	86788-38-7
Molecular Formula	C6H8ClNO2
Molecular Weight	161.59 g/mol
Synonyms	2-Oxopiperidine-1-carbonyl chloride; 1-(Chlorocarbonyl)-2-piperidinone; 2-Piperidinone-1-carbonyl chloride; N-Carboxy-2-piperidonic acid chloride; 1-Piperidinecarbonyl chloride, 2-oxo-; Piperidine-1-carbonyl chloride, 2-oxo-; N-(Chlorocarbonyl)-2-piperidinone
EINECS	Contact for details

Quality Control

Every batch of 1-Piperidinecarbonyl Chloride, 2-Oxo- is manufactured and tested under strict quality management systems. We provide comprehensive analytical documentation to ensure the material meets the precise requirements for research and scale-up applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.