Description

1-Phenyl-1-(4-(Trifluoromethyl)Phenyl)Ethanol is a high-value trifluoromethylated tertiary alcohol that serves as a versatile chiral building block in advanced organic synthesis. Its structure, featuring both aromatic and fluorinated components, is critical for modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, where the trifluoromethyl group enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Asymmetric Catalysis Research: Employed as a test substrate or ligand precursor in the development of new chiral catalysts and methodologies.
• Advanced Polymer Chemistry: Incorporated as a monomer or chain modifier to create specialty polymers with unique thermal and chemical resistance properties.
• Fine Chemical & Flavor/Fragrance Intermediates: Utilized in the multi-step synthesis of complex aromatic compounds for high-value fine chemicals.

Basic Information

Product Name	1-Phenyl-1-(4-(Trifluoromethyl)Phenyl)Ethanol
CAS No.	86767-33-1
Molecular Formula	C15H13F3O
Molecular Weight	266.26 g/mol
Synonyms	α-(4-(Trifluoromethyl)phenyl)benzenemethanol; 1-[4-(Trifluoromethyl)phenyl]-1-phenylethanol; (4-Trifluoromethylphenyl)phenylmethanol; Benzhydrol, 4'-(trifluoromethyl)-; α-Methyl-4'-(trifluoromethyl)benzhydrol; 1-(4-Trifluoromethylphenyl)-1-phenylethanol; TFMPE; 4'-(Trifluoromethyl)benzhydrol
EINECS	Contact for details

Quality Control

Our 1-Phenyl-1-(4-(Trifluoromethyl)Phenyl)Ethanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the stringent requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (Specific enantiomer available)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.