Description

Ganciclovir Triphosphate is a biologically active triphosphate analog of the antiviral nucleoside ganciclovir. This compound is a critical reagent in molecular biology and pharmaceutical research, serving as the active intracellular metabolite responsible for the antiviral activity of its prodrug form. It is primarily utilized by researchers and manufacturers in the fields of virology, biochemistry, and drug discovery. The high-purity material is essential for studies involving DNA polymerase inhibition and antiviral mechanism elucidation.

Application

• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly with viral and cellular DNA polymerases.
• Antiviral Mechanism Studies: Essential for investigating the mode of action and efficacy of ganciclovir and related antiviral compounds.
• Pharmaceutical Reference Standard: Serves as a high-purity analytical standard for quality control and assay development in drug manufacturing.
• Virology and Cell Biology: Employed in research on herpesviruses (CMV, HSV) and other DNA viruses to study viral replication and inhibition.
• Nucleotide Metabolism Research: A key compound for studying the incorporation of nucleotide analogs into DNA and the resulting biological effects.

Basic Information

Product Name	Ganciclovir Triphosphate
CAS No.	86761-38-8
Molecular Formula	C9H16N5O13P3
Molecular Weight	519.15 g/mol
Synonyms	Ganciclovir triphosphate sodium salt; GCV-TP; 9-[(1,3-Dihydroxy-2-propoxy)methyl]guanine triphosphate; 2'-Nor-2'-deoxyguanosine triphosphate; Ganciclovir 5'-triphosphate; NSC 113927; (R)-9-(3,4-Dihydroxybutyl)guanine triphosphate; Ganciclovir TP
EINECS	Contact for details

Quality Control

Our Ganciclovir Triphosphate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry. We provide Certificates of Analysis (COA) with detailed chromatograms and full analytical data to support your research and regulatory requirements. The product is suitable for use as a pharmaceutical reference standard.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.