Description

3-Chlorothiophene-2-Carbonyl Chloride is a high-purity, reactive organic intermediate of significant importance in advanced chemical synthesis. Its value lies in its dual functional groups, making it a versatile building block for constructing complex heterocyclic molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting the central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the thiophene scaffold for bioactivity.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of conductive polymers and advanced organic electronic materials.
• Ligand and Catalyst Development: Employed to synthesize specialized ligands for metal catalysis and organocatalysts used in asymmetric synthesis.
• Custom Synthesis and Contract Manufacturing: A critical raw material for fine chemical manufacturers producing bespoke compounds for client R&D programs.

Basic Information

Product Name	3-Chlorothiophene-2-Carbonyl Chloride
CAS No.	86427-02-3
Molecular Formula	C5H2Cl2OS
Molecular Weight	181.04 g/mol
Synonyms	2-Chlorocarbonyl-3-chlorothiophene; 3-Chloro-2-thiophenecarbonyl chloride; 3-Chlorothiophene-2-carboxylic acid chloride; 3-Chloro-2-thienoyl chloride; 3-Chlorothiophene-2-carbonylchloride; 2,3-Dichlorothiophene-5-carboxylic acid chloride (tautomer); 86427-02-3
EINECS	Contact for details

Quality Control

Our 3-Chlorothiophene-2-Carbonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.