Description

Fluconazole CAS NO 86386-73-4 is a potent synthetic triazole antifungal agent widely recognized for its selective inhibition of fungal cytochrome P450 sterol 14α-demethylase. This compound is critical for ensuring product purity and efficacy in pharmaceutical manufacturing and research. It is an essential raw material for producers of antifungal medications, serving the pharmaceutical, veterinary medicine, and agrochemical industries.

Application

• Pharmaceutical API: Primary active pharmaceutical ingredient (API) in the manufacture of systemic and topical antifungal medications.
• Veterinary Antifungals: Used in formulations to treat fungal infections in companion animals and livestock.
• Agrochemical Research: Serves as a key reference standard and intermediate in the development of novel agricultural fungicides.
• Clinical Diagnostics: Employed as a standard in laboratory assays and microbiological testing for antifungal susceptibility.
• Biochemical Research: A vital tool for studying fungal metabolism, sterol biosynthesis pathways, and mechanisms of drug resistance.
• Formulation Development: Used in R&D for creating new dosage forms such as tablets, capsules, and intravenous solutions.

Basic Information

Product Name	Fluconazole
CAS No.	86386-73-4
Molecular Formula	C13H12F2N6O
Molecular Weight	306.27 g/mol
Synonyms	2-(2,4-Difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-yl)propan-2-ol; Diflucan (trade name); UK-49,858; Biozolene; Elazor; Triflucan; Fluconazol; Flucoral
EINECS	Contact for details

Quality Control

Our Fluconazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, assay, and impurity profiling via HPLC, to ensure it meets high-purity standards suitable for pharmaceutical use. Certificates of Analysis (COA) confirming compliance with in-house specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.