Description

2-Furancarbonyl Chloride, Tetrahydro-2-Methyl-5-Oxo-, (S)- (9Ci) is a high-value, chiral building block characterized by its reactive acid chloride functionality and stereochemical purity. This compound matters for its critical role in the synthesis of complex, optically active molecules, enabling the introduction of specific stereocenters and functional groups. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients, as well as by fine chemical manufacturers producing advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of drugs targeting the central nervous system and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced, stereospecific pesticides and herbicides where the (S)-enantiomer provides the desired biological activity.
• Asymmetric Catalysis Research: Serves as a precursor or ligand component in the development of new chiral catalysts for enantioselective reactions.
• Fine Chemical Manufacturing: Employed in the multi-step synthesis of complex natural products, flavors, and fragrances requiring high stereochemical fidelity.
• Polymer Modification: Acts as a reactive monomer or coupling agent for introducing furan-based moieties into specialty polymers with tailored properties.

Basic Information

Product Name	2-Furancarbonyl Chloride, Tetrahydro-2-Methyl-5-Oxo-, (S)- (9Ci)
CAS No.	86363-00-0
Molecular Formula	C7H9ClO3
Molecular Weight	176.60 g/mol
Synonyms	(S)-Tetrahydro-2-methyl-5-oxo-2-furancarbonyl chloride; (S)-5-Oxotetrahydro-2-methyl-2-furoyl chloride; (S)-2-Methyl-5-oxotetrahydrofuran-2-carbonyl chloride; (S)-α-Methyl-γ-butyrolactone-α-carbonyl chloride; (S)-Mevalonolactone acid chloride; (S)-Methyl Dihydro-5-oxo-2(3H)-furancarboxylate chloride; (3S)-3-Methyl-5-oxodihydrofuran-3-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 2-Furancarbonyl Chloride, Tetrahydro-2-Methyl-5-Oxo-, (S)- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC to ensure high enantiomeric excess (e.e.) and purity verification. Certificates of Analysis (COA) detailing identity, assay, impurity profile, and chiral purity are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic and moisture-sensitive nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.