Description

3-(Trifluoromethoxy)Benzoyl Chloride is a high-purity, reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the unique combination of the benzoyl chloride moiety's reactivity and the trifluoromethoxy group's ability to impart desirable properties like enhanced lipophilicity and metabolic stability to target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to synthesize active ingredients and functional intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring the trifluoromethoxy-phenyl pharmacophore.
• Agrochemical Synthesis: Used in manufacturing herbicides, fungicides, and insecticides, where the trifluoromethoxy group can improve biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a building block for advanced organic materials, including liquid crystals for display technologies.
• Polymer Chemistry: Employed as a monomer or modifying agent to introduce specific functional groups into polymer chains, enhancing material properties.
• Organic Synthesis Reagent: A versatile reagent for Friedel-Crafts acylation and nucleophilic acyl substitution reactions to form amides, esters, and ketones.
• Chemical Research & Development: Fundamental reagent in medicinal chemistry and material science R&D for creating novel compound libraries.

Basic Information

Product Name	3-(Trifluoromethoxy)Benzoyl Chloride
CAS No.	86270-03-3
Molecular Formula	C8H4ClF3O2
Molecular Weight	224.56 g/mol
Synonyms	m-(Trifluoromethoxy)benzoyl chloride; 3-(Trifluoromethoxy)benzoic acid chloride; α,α,α-Trifluoro-m-anisoyl chloride; Benzoyl chloride, 3-(trifluoromethoxy)-; 3-Trifluoromethoxybenzoyl chloride; m-Trifluoromethoxybenzoyl chloride
EINECS	Contact for details

Quality Control

Our production of 3-(Trifluoromethoxy)Benzoyl Chloride adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability. Each lot undergoes comprehensive analytical testing, including assay by GC/HPLC, identity confirmation (IR, NMR), and impurity profiling. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support compliance with global regulatory frameworks, including REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and reacts vigorously with water, strong bases, and alcohols. Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent hydrolysis. Isolate from incompatible materials such as strong oxidizers and amines.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.