Description

4-Fluoro-3-(Trifluoromethoxy)-Benzenemethanol is a high-value fluorinated aromatic building block characterized by its unique trifluoromethoxy and fluorobenzyl alcohol functional groups. This compound is essential for introducing specific steric and electronic properties into target molecules, enhancing their metabolic stability and lipophilicity. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for CNS-targeted therapies and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atoms contribute to improved biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for high-performance displays.
• Organic Electronics: Employed in the synthesis of charge-transport materials and semiconductors for OLEDs and organic photovoltaics.
• Advanced Polymer Modification: Acts as a monomer or modifier to introduce fluorine into polymer backbones, enhancing chemical resistance and thermal stability.
• Chemical Research & Development: A versatile building block for medicinal chemistry and material science exploration in academic and industrial labs.

Basic Information

Product Name	4-Fluoro-3-(Trifluoromethoxy)-Benzenemethanol
CAS No.	86256-18-0
Molecular Formula	C8H6F4O2
Molecular Weight	210.13 g/mol
Synonyms	4-Fluoro-3-(trifluoromethoxy)benzyl alcohol; (4-Fluoro-3-(trifluoromethoxy)phenyl)methanol; 1-(4-Fluoro-3-(trifluoromethoxy)phenyl)methanol; α,α,α-Trifluoro-4-fluoro-3-methoxybenzyl alcohol; Benzenemethanol, 4-fluoro-3-(trifluoromethoxy)-; 86256-18-0; 4-Fluoro-α,α,α-trifluoro-3-methoxybenzyl alcohol
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-(Trifluoromethoxy)-Benzenemethanol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and batch-to-batch consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.