Description

(11B)-11,17,18,21-Tetrahydroxy-Pregn-4-Ene-3,20-Dione CAS NO 86002-90-6 is a high-purity synthetic steroid derivative, specifically a polyhydroxylated pregnane. This compound is of significant value as a key pharmaceutical intermediate and a reference standard for analytical and research purposes. It is primarily required by manufacturers and research institutions in the pharmaceutical, biotechnology, and life sciences sectors for the development and quality control of steroid-based therapeutics.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of more complex steroid-based active pharmaceutical ingredients (APIs).
• Reference Standard: Used as a certified reference material (CRM) in analytical laboratories for method development, validation, and quality assurance testing.
• Biochemical Research: Employed in metabolic pathway studies, enzyme inhibition assays, and receptor binding studies due to its specific steroid structure.
• Steroid Chemistry Development: Acts as a starting material or model compound for the research and development of novel steroid derivatives with potential therapeutic applications.

Basic Information

Product Name	(11B)-11,17,18,21-Tetrahydroxy-Pregn-4-Ene-3,20-Dione
CAS No.	86002-90-6
Molecular Formula	C21H30O6
Molecular Weight	378.46 g/mol
Synonyms	11β,17α,18,21-Tetrahydroxypregn-4-ene-3,20-dione; 11β,17α,18,21-Tetrahydroxyprogesterone; 18-Hydroxycorticosterone; 18-Hydroxycortisol; 11β,17α,18,21-Tetrahydroxy-4-pregnene-3,20-dione; 18-OH-Cortisol; 18-Hydroxy Compound S; 18-Hydroxy Reichstein's Substance S
EINECS	Contact for details

Quality Control

Our (11B)-11,17,18,21-Tetrahydroxy-Pregn-4-Ene-3,20-Dione is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical intermediates and reference materials. Certificates of Analysis (COA) with detailed HPLC/GC data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.