Description

11Beta,17,21-Trihydroxypregna-1,4-Diene-3,20-Dione 21-Octanoate is a synthetic corticosteroid derivative, specifically a 21-octanoate ester of a prednisolone analogue. This compound matters as a key pharmaceutical intermediate, offering a modified pharmacokinetic profile for enhanced drug delivery and efficacy in therapeutic formulations. It is primarily needed by manufacturers in the pharmaceutical and life science research sectors for the development of advanced anti-inflammatory and immunosuppressive medications.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of advanced corticosteroid APIs (Active Pharmaceutical Ingredients).
• Anti-inflammatory Drug Development: Used in R&D for creating novel topical and systemic anti-inflammatory agents with optimized release profiles.
• Immunosuppressive Therapy Research: Serves as a precursor in studies for medications targeting autoimmune diseases and preventing organ transplant rejection.
• Veterinary Medicine: Potential application in formulating long-acting corticosteroid treatments for animals.
• Biochemical Research: Used as a reference standard or tool compound in studying glucocorticoid receptor interactions and metabolic pathways.
• Prodrug Synthesis: Its esterified structure makes it valuable for designing prodrugs aimed at improving bioavailability and targeted delivery.

Basic Information

Product Name	11Beta,17,21-Trihydroxypregna-1,4-Diene-3,20-Dione 21-Octanoate
CAS No.	85959-58-6
Molecular Formula	C29H40O7
Molecular Weight	500.63 g/mol
Synonyms	Prednisolone 21-Octanoate; 11β,17,21-Trihydroxypregna-1,4-diene-3,20-dione 21-octanoate; 21-Octanoyloxyprednisolone; NSC 106977; UNII-9J4865IF1C; Prednisolone Caprylate; 21-(Octanoyloxy)prednisolone
EINECS	Contact for details

Quality Control

Our 11Beta,17,21-Trihydroxypregna-1,4-Diene-3,20-Dione 21-Octanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets high-grade standards suitable for pharmaceutical R&D and intermediate synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.