Description

Cremophor (R) A6 is a non-ionic surfactant and solubilizer belonging to the polyoxyl castor oil derivative family. It is a critical excipient used to enhance the solubility and bioavailability of poorly water-soluble active pharmaceutical ingredients (APIs). This high-purity grade is essential for formulators in the pharmaceutical and cosmetic industries seeking reliable, consistent performance in injectable, oral, and topical formulations.

Application

• Pharmaceutical Solubilizer: Key excipient for formulating injectable and oral drugs with low aqueous solubility.
• Lipid-based Drug Delivery Systems: Used in self-emulsifying drug delivery systems (SEDDS) and microemulsions.
• Cosmetic & Personal Care Formulations: Acts as an emulsifier and solubilizer for fragrances, oils, and vitamins in creams and lotions.
• Vitamin & Nutritional Supplement Formulations: Improves the dispersion of fat-soluble vitamins (A, D, E, K) in liquid supplements.
• Agricultural & Pesticide Adjuvants: Enhances the solubility and stability of active agrochemical ingredients.
• Industrial Applications: Used as a surfactant in specialty coatings, textile processing, and chemical synthesis.

Basic Information

Product Name	Cremophor (R) A6
CAS No.	85941-44-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Polyoxyl 6 Hydrogenated Castor Oil; PEG-6 Hydrogenated Castor Oil; Macrogol 6 Hydrogenated Castor Oil; Polyoxyethylene (6) Hydrogenated Castor Oil; Kolliphor (R) RH40 (related grade); Nonionic Surfactant A6; Hydrogenated Castor Oil Ethoxylate (6 EO); Solubilizer A6
EINECS	Contact for details

Quality Control

Our Cremophor A6 is manufactured under a strict quality management system and is suitable for pharmaceutical applications. Each batch is tested to ensure it meets relevant specifications for identity, assay, and critical impurities. A comprehensive Certificate of Analysis (COA) documenting purity, physicochemical properties, and compliance is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms
Assay (Oxirane Oxygen)	Contact for details
Hydroxyl Value	Contact for details
Saponification Value	Contact for details
Acid Value	≤ 2.0 mg KOH/g
Water Content (KF)	≤ 1.0 %
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.