Description

(22R,23R,24E)-2α,3α,22,23-Tetrahydroxy-24-Ethylidene-5α-Cholestan-6-One is a high-purity, multi-hydroxylated steroidal ketone of significant interest in advanced chemical synthesis and life science research. This compound serves as a critical chiral intermediate for the development of complex bioactive molecules, offering precise stereochemical control. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and manufacturers of fine chemicals and reference standards.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel steroidal drugs and bioactive compounds.
• Biochemical Research: Used as a reference standard or precursor in studies of sterol biosynthesis, metabolism, and enzyme inhibition.
• Fine Chemical Synthesis: Serves as a sophisticated starting material for creating complex natural product analogs and specialty chemicals.
• Reference Standard: Employed in analytical method development and validation for quality control laboratories.
• Academic & Discovery Chemistry: A valuable tool for exploring new synthetic pathways and structure-activity relationships (SAR).

Basic Information

Product Name	(22R,23R,24E)-2α,3α,22,23-Tetrahydroxy-24-Ethylidene-5α-Cholestan-6-One
CAS No.	85797-14-4
Molecular Formula	C₂₉H₄₈O₅
Molecular Weight	476.70 g/mol
Synonyms	2α,3α,22,23-Tetrahydroxy-24-ethylidene-5α-cholestan-6-one; (22R,23R)-2α,3α,22,23-Tetrahydroxy-24-methylene-5α-cholestan-6-one; 24-Ethylidene-2α,3α,22,23-tetrahydroxy-5α-cholestan-6-one; Brassinolide precursor; Steroidal polyol ketone; 5α-Cholestan-6-one, 2α,3α,22,23-tetrahydroxy-24-ethylidene-, (22R,23R,24E)-
EINECS	Contact for details

Quality Control

Every batch of our (22R,23R,24E)-2α,3α,22,23-Tetrahydroxy-24-Ethylidene-5α-Cholestan-6-One undergoes rigorous analytical testing to ensure identity, purity, and consistency. We adhere to stringent internal quality standards suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% (22R,23R,24E)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.