Description

2-Bromo-4-(Trifluoromethyl)Benzoyl Chloride is a high-value, reactive aromatic acid chloride derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both bromine and trifluoromethyl substituents, makes it an indispensable precursor for introducing specific functionalities into target molecules. This compound is primarily sought after by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring bromo- and trifluoromethyl-phenyl motifs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science: Employed in the synthesis of monomers and polymers with unique electronic or surface properties.
• Custom Synthesis and Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.
• Research & Development: Essential for medicinal chemistry programs exploring structure-activity relationships (SAR) and for developing new synthetic methodologies.

Basic Information

Item	Details
Product Name	2-Bromo-4-(Trifluoromethyl)Benzoyl Chloride
CAS No.	85663-09-8
Molecular Formula	C8H3BrClF3O
Molecular Weight	287.46 g/mol
Synonyms	2-Bromo-α,α,α-trifluoro-p-toluoyl Chloride; 2-Bromo-4-(trifluoromethyl)benzoic acid chloride; α,α,α-Trifluoro-2-bromo-4-methylbenzoyl Chloride; Benzoyl chloride, 2-bromo-4-(trifluoromethyl)-; 4-(Trifluoromethyl)-2-bromobenzoyl chloride; 2-Bromo-4-trifluoromethylbenzoyl chloride; p-Trifluoromethyl-o-bromobenzoyl chloride
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-(Trifluoromethyl)Benzoyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay and impurity profiles. We support compliance with global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.