Description

cis-2-(2,4-Dichlorophenyl)-2-(1H-Imidazol-1-Ylmethyl)-1,3-Dioxolan-4-Ylmethyl Toluene-p-Sulphonate is a high-purity, advanced pharmaceutical intermediate with a complex molecular architecture. This compound is critical for the synthesis of active pharmaceutical ingredients (APIs), particularly in the antifungal and agrochemical sectors, where precise chemical structure is paramount for efficacy. It is primarily sought by research institutions, fine chemical manufacturers, and pharmaceutical companies engaged in the development of novel therapeutic and crop protection agents.

Application

• Key Intermediate for Antifungal APIs: Serves as a crucial building block in the synthesis of potent imidazole-based antifungal agents.
• Agrochemical Synthesis: Used in the research and production of advanced fungicides and pesticides for crop protection.
• Organic Synthesis Research: A valuable substrate for developing new synthetic methodologies involving dioxolane and imidazole chemistry.
• Pharmaceutical R&D: Employed in medicinal chemistry programs for creating new molecular entities targeting fungal infections.
• Fine Chemical Manufacturing: Supplied to custom synthesis and contract manufacturing organizations (CMOs) for scale-up production.

Basic Information

Product Name	cis-2-(2,4-Dichlorophenyl)-2-(1H-Imidazol-1-Ylmethyl)-1,3-Dioxolan-4-Ylmethyl Toluene-p-Sulphonate
CAS No.	85650-50-6
Molecular Formula	C21H20Cl2N2O5S
Molecular Weight	491.36 g/mol
Synonyms	cis-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-ylmethyl 4-methylbenzenesulfonate; 1,3-Dioxolane-4-methanol, 2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-, 4-methylbenzenesulfonate (ester), cis-; Toluene-4-sulfonic acid cis-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-ylmethyl ester; Ketoconazole intermediate; cis-Dioxolane imidazole tosylate; 85650-50-6 (CAS Name).
EINECS	Contact for details

Quality Control

Our cis-2-(2,4-Dichlorophenyl)-2-(1H-Imidazol-1-Ylmethyl)-1,3-Dioxolan-4-Ylmethyl Toluene-p-Sulphonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.