Description

(17S,22R,25R)-14,17,20,22,28-Pentahydroxy-1-Oxoergosta-2,5-Dien-26-Oic Acid 26,28-Lactone is a complex, polyhydroxylated ergostane-type steroidal lactone with significant biological activity. This compound matters as a high-value pharmaceutical intermediate and a key scaffold for research into novel therapeutic agents. It is primarily needed by pharmaceutical R&D and biochemical synthesis laboratories focused on developing anti-inflammatory, anti-cancer, or metabolic regulators.

Application

• Pharmaceutical Intermediate: Serves as a critical building block for the synthesis of novel steroidal drugs and bioactive molecules.
• Biochemical Research: Used as a reference standard or probe in studies of enzyme inhibition, receptor binding, and signal transduction pathways.
• Natural Product Synthesis: Acts as a key precursor in the semi-synthesis or total synthesis of complex natural products with ergostane skeletons.
• Anti-inflammatory Agent Development: Investigated for its potential to modulate inflammatory responses due to its structural similarity to other bioactive sterols.
• Academic Research: Utilized in university and institutional labs for chemical education and advanced organic chemistry projects.

Basic Information

Product Name	(17S,22R,25R)-14,17,20,22,28-Pentahydroxy-1-Oxoergosta-2,5-Dien-26-Oic Acid 26,28-Lactone
CAS No.	85643-90-9
Molecular Formula	C₂₈H₄₀O₈
Molecular Weight	504.62 g/mol
Synonyms	14,17,20,22,28-Pentahydroxy-1-oxoergosta-2,5-dien-26-oic acid 26,28-lactone; (17S,22R,25R)-Pentahydroxy-oxoergostadienoic acid lactone; Ergosta-2,5-dien-26-oic acid, 14,17,20,22,28-pentahydroxy-1-oxo-, 26,28-lactone, (17S,22R,25R)-; Steroidal pentahydroxy lactone; Polyhydroxylated ergostane lactone
EINECS	Contact for details

Quality Control

Our (17S,22R,25R)-14,17,20,22,28-Pentahydroxy-1-Oxoergosta-2,5-Dien-26-Oic Acid 26,28-Lactone is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. All products undergo rigorous analytical testing, including HPLC and NMR, to verify identity and potency. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical methods is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.