Description

Pyrrolidine-1-Butyryl Chloride Hydrochloride is a versatile and highly reactive organic building block, primarily used as an acylating agent in advanced chemical synthesis. Its core value proposition lies in enabling the efficient introduction of the pyrrolidine-1-butyryl moiety, a key structural feature in various pharmacologically active compounds. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly those developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting neurological and cardiovascular disorders.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, leveraging its reactive chloride group.
• Peptide Chemistry: Serves as an acylating agent for modifying amino acids or peptides to alter their biological activity or stability.
• Material Science Research: Employed in the creation of specialized polymers and functional materials with tailored properties.
• Chemical Biology Probes: Useful for labeling biomolecules or creating probe molecules for studying biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical reagent for CDMOs (Contract Development and Manufacturing Organizations) producing custom fine chemicals for clients.

Basic Information

Product Name	Pyrrolidine-1-Butyryl Chloride Hydrochloride
CAS No.	85614-46-6
Molecular Formula	C8H15Cl2NO
Molecular Weight	212.12 g/mol
Synonyms	1-Butanoyl chloride, 1-pyrrolidinyl-, hydrochloride; 1-Pyrrolidinebutyryl chloride hydrochloride; 4-(Pyrrolidin-1-yl)butanoyl chloride hydrochloride; N-Butyryl chloride pyrrolidine hydrochloride; Pyrrolidine, 1-(3-chloroformylpropyl)-, hydrochloride; 1-(3-Chlorocarbonylpropyl)pyrrolidinium chloride
EINECS	Contact for details

Quality Control

Our Pyrrolidine-1-Butyryl Chloride Hydrochloride is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. We adhere to cGMP standards where applicable to support our clients in regulated markets.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.