Description

Zaltidine is a selective histamine H2-receptor antagonist with potent antisecretory activity. This compound is a critical pharmaceutical intermediate in the synthesis of advanced therapeutic agents targeting gastric acid-related disorders. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development and production of novel gastrointestinal medications. The material is supplied as a high-purity building block to ensure consistency and efficacy in downstream synthetic processes.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of histamine H2-receptor antagonist drugs.
• Gastrointestinal Drug Research: Used in preclinical and clinical research for developing new anti-ulcer and acid-suppression therapies.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a precursor in the multi-step manufacturing of final drug substances.
• Biochemical Research: Employed in studies investigating histamine receptor mechanisms and signal transduction pathways.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	Zaltidine
CAS No.	85604-00-8
Molecular Formula	C13H16N4O3S
Molecular Weight	308.36 g/mol
Synonyms	Zaltidine; ICI 125,211; 2-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]-N-(2-aminoethyl)acetamide; SK&F 95282; Zaltidine Hydrochloride (salt form); 1-[2-[[[2-[(Diaminomethylideneamino)-1,3-thiazol-4-yl]methyl]sulfanyl]acetyl]amino]ethyl]guanidine
EINECS	Contact for details

Quality Control

Our Zaltidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via HPLC, to ensure it meets stringent specifications for pharmaceutical intermediate use. Certificates of Analysis (COA) documenting all test results are provided with every shipment to guarantee traceability and compliance with cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.