Description

(3α,5β,7α,12α,24E)-3,7,12-Trihydroxy-Cholest-24-En-26-Oic Acid is a high-purity, modified bile acid derivative with significant research and pharmaceutical development potential. This compound serves as a critical intermediate and reference standard for synthesizing novel therapeutic agents and studying metabolic pathways. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on steroid chemistry, hepatoprotective agents, and metabolic disorder research.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel bile acid analogs and hepatoprotective drugs.
• Biochemical Research: Used as a reference standard and probe in studies of bile acid metabolism, liver function, and nuclear receptor (e.g., FXR) signaling pathways.
• Reference Material: Serves as a high-purity certified reference material (CRM) for analytical method development and validation in quality control laboratories.
• Fine Chemical Synthesis: Intermediate for the production of more complex steroid derivatives and specialized chiral compounds.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic chemistry, medicinal chemistry, and biochemistry.

Basic Information

Product Name	(3α,5β,7α,12α,24E)-3,7,12-Trihydroxy-Cholest-24-En-26-Oic Acid
CAS No.	85552-38-1
Molecular Formula	C27H44O5
Molecular Weight	448.64 g/mol
Synonyms	3α,7α,12α-Trihydroxy-5β-cholest-24-en-26-oic Acid; 3α,7α,12α-Trihydroxy-5β-cholestenoic Acid; (24E)-3α,7α,12α-Trihydroxy-5β-cholest-24-en-26-oic Acid; 5β-Cholest-24-ene-26-oic acid, 3,7,12-trihydroxy-, (3α,5β,7α,12α,24E)-; Trihydroxycholestenecarboxylic Acid
EINECS	Contact for details

Quality Control

Our (3α,5β,7α,12α,24E)-3,7,12-Trihydroxy-Cholest-24-En-26-Oic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.