Description

7-(6'-Deoxy-β-D-Allofuranosyl)Guanine is a specialized nucleoside analogue with significant research and pharmaceutical development potential. This compound matters as a key intermediate or reference standard in the synthesis of novel antiviral and anticancer agents, particularly those targeting viral polymerases and cellular DNA replication. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions focused on nucleoside chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of advanced nucleoside-based therapeutics.
• Antiviral Research: Used in the development and study of potential antiviral compounds targeting DNA viruses.
• Oncology Research: Investigated as a precursor for chemotherapeutic agents that interfere with DNA synthesis in cancer cells.
• Biochemical Research: Functions as a substrate or inhibitor in enzymatic studies involving polymerases and kinases.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Process Development: Utilized in scaling up synthetic routes for novel nucleoside drugs under Good Manufacturing Practice (GMP) conditions.

Basic Information

Product Name	7-(6'-Deoxy-β-D-Allofuranosyl)Guanine
CAS No.	85421-88-1
Molecular Formula	C₁₁H₁₅N₅O₄
Molecular Weight	281.27 g/mol
Synonyms	7-(6-Deoxy-β-D-allofuranosyl)guanine; 6'-Deoxy-β-D-allofuranosylguanine; Guanosine analogue, 6'-deoxy-allofuranosyl; 9-[(2S,3S,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,9-dihydro-6H-purin-6-one; 7-(6-Deoxy-β-D-allo-furanosyl)guanine
EINECS	Contact for details

Quality Control

Our 7-(6'-Deoxy-β-D-Allofuranosyl)Guanine is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Quality is verified through advanced analytical techniques including HPLC, NMR, and mass spectrometry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.