Description

Diethyl[4-(1,3-Dioxolan-2-Yl)Phenyl]Phosphonate is a high-value organophosphorus compound featuring a protected aldehyde functionality, making it a versatile synthetic intermediate. Its core value lies in enabling precise chemical transformations for the construction of complex molecules, particularly in pharmaceutical and agrochemical research. This compound is essential for chemists and manufacturers in fine chemical synthesis, advanced material science, and life sciences who require reliable, high-purity building blocks for their development pipelines.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing arylphosphonate or benzaldehyde motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators that utilize phosphonate chemistry.
• Ligand and Catalyst Precursor: Serves as a precursor for the synthesis of specialized phosphonate-based ligands used in metal-catalyzed coupling reactions.
• Material Science Research: Employed in the development of advanced polymers, flame retardants, and specialty materials where the phosphonate group imparts specific properties.
• Organic Synthesis Building Block: Utilized in Horner-Wadsworth-Emmons (HWE) olefination reactions to generate alkenes, a fundamental transformation in complex molecule assembly.
• Chemical Biology Probes: Acts as a starting material for creating molecular probes and inhibitors that target phosphate-binding biological sites.

Basic Information

Product Name	Diethyl[4-(1,3-Dioxolan-2-Yl)Phenyl]Phosphonate
CAS No.	85416-98-4
Molecular Formula	C₁₃H₁₉O₅P
Molecular Weight	286.26 g/mol
Synonyms	Diethyl (4-(1,3-dioxolan-2-yl)phenyl)phosphonate; [4-(1,3-Dioxolan-2-yl)phenyl]phosphonic Acid Diethyl Ester; Diethyl P-[4-(1,3-dioxolan-2-yl)phenyl]phosphonate; 2-[4-(Diethoxyphosphoryl)phenyl]-1,3-dioxolane; (4-(1,3-Dioxolan-2-yl)phenyl)phosphonic Acid Diethyl Ester; Diethyl 4-(1,3-Dioxolan-2-yl)benzylphosphonate (common name variant); Phosphonic acid, P-[4-(1,3-dioxolan-2-yl)phenyl]-, diethyl ester
EINECS	Contact for details

Quality Control

Our Diethyl[4-(1,3-Dioxolan-2-Yl)Phenyl]Phosphonate is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize moisture exposure. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.