Description

Rilmenidine Phosphate is a high-purity, non-imidazoline antihypertensive agent used as a key pharmaceutical intermediate and active ingredient. Its primary value lies in its selective I1-imidazoline receptor agonist activity, which offers a favorable side-effect profile for blood pressure management. This compound is essential for manufacturers in the pharmaceutical industry engaged in the research, development, and production of cardiovascular medications. Rilmenidine Phosphate CAS NO 85409-38-7 is supplied under stringent quality controls to ensure reliability for critical synthesis processes.

Application

• Pharmaceutical Active Ingredient (API): Primary use in the formulation of antihypertensive drugs.
• Research & Development: Critical reference standard and building block in cardiovascular drug discovery programs.
• Process Chemistry: Serves as a key intermediate in the multi-step synthesis of finished dosage forms.
• Analytical Testing: Used as a certified reference material (CRM) for method development and validation in QC laboratories.
• Clinical Trial Material (CTM) Manufacturing: Supplied under GMP guidelines for the production of batches for clinical studies.
• Generic Drug Manufacturing: A vital component for companies developing bioequivalent versions of branded rilmenidine-based medications.

Basic Information

Item	Details
Product Name	Rilmenidine Phosphate
CAS No.	85409-38-7
Molecular Formula	C10H19N2O2 • H3PO4
Molecular Weight	326.26 g/mol
Synonyms	Rilmenidine Dihydrogen Phosphate; (N-Dicyclopropylmethyl)-4,5-dihydro-2-oxazolamine Phosphate; S 3341; S-3341; S3341; 2-[(Dicyclopropylmethyl)amino]-4,5-dihydro-1,3-oxazole Phosphate; Tenaxum
EINECS	Contact for details

Quality Control

Our Rilmenidine Phosphate is manufactured and tested to meet exacting standards suitable for pharmaceutical applications. Quality assurance protocols are designed to ensure identity, purity, strength, and composition. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing results from tests including HPLC assay, related substances, and residual solvent analysis. We support compliance with ICH Q7 guidelines and can supply material aligned with customer-specific pharmacopeial requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.