Description

4,5-Epoxyestrene-3-One-17-Ol is a high-purity steroidal epoxide and a key synthetic intermediate in organic chemistry. This compound is valued for its defined stereochemistry and reactive epoxide functionality, which enables precise chemical transformations in complex synthesis pathways. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers for the development and production of advanced steroid-based active pharmaceutical ingredients (APIs) and other specialized bioactive molecules.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of novel steroid-based therapeutics and hormonal agents.
• Research & Development: Used in academic and industrial R&D settings for exploring new synthetic routes and studying structure-activity relationships (SAR) of steroidal compounds.
• Fine Chemical Synthesis: Serves as a precursor for manufacturing high-value, specialized fine chemicals with steroidal backbones.
• Reference Standard: Can be utilized as an analytical reference standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	4,5-Epoxyestrene-3-One-17-Ol
CAS No.	85382-36-1
Molecular Formula	C₁₉H₂₆O₃
Molecular Weight	302.41 g/mol
Synonyms	17β-Hydroxy-4,5α-epoxyestr-3-one; 4,5α-Epoxy-17β-hydroxyestr-3-one; 4,5-Epoxy-17β-hydroxyestr-3-one; 4,5α-Epoxy-17β-hydroxyestran-3-one; 17β-Hydroxy-4,5α-epoxyestran-3-one; 4,5-Epoxy-17β-hydroxy-3-oxoestrane
EINECS	Contact for details

Quality Control

Our 4,5-Epoxyestrene-3-One-17-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical intermediate applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.