Description

3-Thiophenecarbonylchloride,2-Chloro-4-Methyl-(9Ci) is a specialized heterocyclic building block and acid chloride derivative, identified by CAS number 85345-23-9. This compound is a critical intermediate for synthesizing complex molecules, offering a reactive site for amide and ester formation. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS and anti-infective therapies.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that incorporate the thiophene moiety for enhanced activity.
• Material Science Research: Serves as a monomer or precursor in the development of conductive polymers, organic semiconductors, and advanced organic electronic materials.
• Chemical Biology & Proteomics: Employed as a reagent for modifying peptides, proteins, or other biomolecules to introduce fluorescent tags or affinity labels via its reactive acid chloride group.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.
• Academic Research: Utilized in university and institutional laboratories for fundamental studies in organic synthesis methodology and heterocyclic chemistry.

Basic Information

Product Name	3-Thiophenecarbonylchloride,2-Chloro-4-Methyl-(9Ci)
CAS No.	85345-23-9
Molecular Formula	C6H4Cl2OS
Molecular Weight	195.07 g/mol
Synonyms	2-Chloro-4-methylthiophene-3-carbonyl chloride; 2-Chloro-4-methyl-3-thiophenecarbonyl chloride; 3-Thenoyl chloride, 2-chloro-4-methyl-; 2-Chloro-4-methyl-3-thienoyl chloride; 85345-23-9; 2-Chloro-4-methylthiophene-3-carboxylic acid chloride; 4-Methyl-2-chlorothiophene-3-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 3-Thiophenecarbonylchloride,2-Chloro-4-Methyl-(9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its nature as a strong acid/organic solvent derivative, it should be kept away from moisture, strong bases, and oxidizing agents. Use appropriate corrosion-resistant storage materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.