Description

5-(4-Hydroxybutyn-1-Yl)Uridine is a modified nucleoside analog of significant interest in advanced pharmaceutical and biochemical research. This compound matters as a key synthetic intermediate and building block for the development of novel therapeutic agents and diagnostic probes. It is primarily needed by research institutions and pharmaceutical companies engaged in nucleoside chemistry, antiviral drug discovery, and the synthesis of oligonucleotide-based therapeutics.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used in studies investigating nucleoside metabolism, enzyme mechanisms, and as a substrate for specific kinases or transferases.
• Oligonucleotide Synthesis: Serves as a modified monomer for the preparation of labeled or functionally enhanced DNA/RNA strands for diagnostic and therapeutic applications.
• Pro-drug Development: Utilized in the design and synthesis of nucleoside pro-drugs to improve bioavailability and targeting.
• Labeling and Tracing: Acts as a precursor for the incorporation of reporter groups or isotopes into nucleic acid sequences.

Basic Information

Product Name	5-(4-Hydroxybutyn-1-Yl)Uridine
CAS No.	85267-67-0
Molecular Formula	C13H18N2O7
Molecular Weight	314.29 g/mol
Synonyms	5-(4-Hydroxy-1-butynyl)uridine; Uridine, 5-(4-hydroxy-1-butynyl)-; 5-(4-Hydroxybut-1-yn-1-yl)uridine; 5-(4-Hydroxybut-1-ynyl)uridine; 5-(4-Hydroxybutynyl)uridine; 5-(4'-Hydroxybutyn-1'-yl)uridine; 5-(ω-Hydroxybutynyl)uridine
EINECS	Contact for details

Quality Control

Our 5-(4-Hydroxybutyn-1-Yl)Uridine is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles for the production of pharmaceutical intermediates, and specifications can be tailored to meet specific research or development project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.