Description

[2R-[2R*(4R*,8R*)]]-3,4-Dihydro-2,5,7,8-Tetramethyl-2-(4,8,12-Trimethyltridecyl)-2H-1-Benzopyran-6-Yl 5-Oxo-L-Prolinate is a high-purity, stereochemically defined derivative of Vitamin E (tocopherol) conjugated with L-proline. This compound is valued for its enhanced stability and targeted biological activity compared to standard tocopherol forms. It is primarily sought by manufacturers in the pharmaceutical, nutraceutical, and advanced cosmetic industries for research and formulation of premium antioxidant and anti-aging products.

Application

• Pharmaceutical Intermediates: Serves as a key chiral building block in the synthesis of novel therapeutic agents targeting oxidative stress.
• Nutraceutical Formulations: Used in high-end dietary supplements for its potent and stabilized antioxidant properties, often in capsule or softgel forms.
• Cosmetic Actives: Incorporated into anti-aging serums, creams, and lotions for skin protection and rejuvenation.
• Biochemical Research: Employed as a standard or reagent in studies of lipid peroxidation, cellular protection, and free radical chemistry.
• Advanced Food Fortification: Potential use in specialized food products requiring a highly stable form of Vitamin E.
• Veterinary Pharmaceuticals: Used in developing health supplements and treatments for animals.

Basic Information

Product Name	[2R-[2R*(4R*,8R*)]]-3,4-Dihydro-2,5,7,8-Tetramethyl-2-(4,8,12-Trimethyltridecyl)-2H-1-Benzopyran-6-Yl 5-Oxo-L-Prolinate
CAS No.	85153-86-2
Molecular Formula	C38H61NO5
Molecular Weight	611.90 g/mol
Synonyms	Vitamin E Prolinate; d-α-Tocopheryl L-Prolinate; (2R)-2,5,7,8-Tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-chromen-6-yl 5-oxo-L-prolinate; Tocopherol Prolinate; 5-Oxo-L-proline, 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydro-2H-1-benzopyran-6-yl ester, [2R-[2R*(4R*,8R*)]]-; L-Prolinic acid, 5-oxo-, ester with 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-6-chromanol; Antioxidant Ester Prolinate
EINECS	Contact for details

Quality Control

Our [2R-[2R*(4R*,8R*)]]-3,4-Dihydro-2,5,7,8-Tetramethyl-2-(4,8,12-Trimethyltridecyl)-2H-1-Benzopyran-6-Yl 5-Oxo-L-Prolinate is manufactured under strict quality systems. Each batch is tested to ensure high chemical purity, correct stereochemistry, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing identity, assay, chiral purity, and related substances by HPLC is provided to guarantee consistent quality and traceability for your regulatory and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from heat and incompatible materials. For long-term storage, consider freezing at -20°C.

Specification

Item	Specification
Appearance	White to pale yellow powder or crystals
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% (by Chiral HPLC)
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.