Description

3,4-Difluorobenzyl Alcohol is a versatile fluorinated aromatic building block of significant importance in advanced organic synthesis. Its value lies in the unique reactivity imparted by the benzyl alcohol group and the strategic placement of fluorine atoms on the aromatic ring, enabling precise modifications to molecular properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require high-purity intermediates for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity, metabolic stability, and lipophilicity.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated components in electronic display technologies and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifier: Incorporated into specialty polymers to alter thermal stability, chemical resistance, and surface properties.
• Cross-coupling Reactions: The benzyl alcohol moiety can be transformed into various functional groups, making it a valuable substrate in Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions.
• Ligand & Catalyst Development: Utilized in the synthesis of novel chiral ligands and organocatalysts for asymmetric synthesis.

Basic Information

Product Name	3,4-Difluorobenzyl Alcohol
CAS No.	85118-05-4
Molecular Formula	C7H6F2O
Molecular Weight	144.12 g/mol
Synonyms	(3,4-Difluorophenyl)methanol; 3,4-Difluorobenzenemethanol; α,3,4-Trifluoro-p-tolyl Alcohol; 3,4-DFBA; 85118-05-4; Benzenemethanol, 3,4-difluoro-; 3,4-Difluorobenzylalcohol
EINECS	Contact for details

Quality Control

Our 3,4-Difluorobenzyl Alcohol is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure it meets the highest standards of purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with each shipment to guarantee traceability and support your regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.