Description

3-Isothiocyanato-Tetrahydro-Thiophene 1,1-Dioxide is a specialized heterocyclic building block featuring both an isothiocyanate and a sulfone functional group, making it a highly reactive and versatile intermediate for advanced synthesis. This compound is critical for the development of novel pharmaceuticals and agrochemicals, particularly in the creation of sulfonylurea and thiourea derivatives with targeted biological activity. It is primarily sought after by research and development chemists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially those containing sulfonylurea or thiourea moieties for diabetes, cancer, or antimicrobial therapies.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging its reactive sites to create compounds with specific modes of action.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry and organic synthesis for exploring new chemical spaces and structure-activity relationships (SAR).
• Material Science Precursor: Potential monomer or cross-linking agent in the development of specialty polymers and functional materials with unique properties.
• Bioconjugation Reagent: The isothiocyanate group can react with amines, making it useful for labeling proteins, peptides, or other biomolecules in biochemical research.

Basic Information

Product Name	3-Isothiocyanato-Tetrahydro-Thiophene 1,1-Dioxide
CAS No.	85109-44-0
Molecular Formula	C5H7NO2S2
Molecular Weight	177.24 g/mol
Synonyms	3-Isothiocyanatotetrahydrothiophene 1,1-Dioxide; Tetrahydro-3-isothiocyanatothiophene 1,1-Dioxide; 3-Isothiocyanato-1,1-dioxotetrahydrothiophene; Thiophene, tetrahydro-3-isothiocyanato-, 1,1-dioxide; Sulfolane-3-isothiocyanate
EINECS	Contact for details

Quality Control

Our 3-Isothiocyanato-Tetrahydro-Thiophene 1,1-Dioxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. Keep away from incompatible materials such as strong bases, amines, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.