Description

3,3-Dimethylbicyclo[2.2.1]heptane-2-propionyl chloride is a specialized organic building block featuring a rigid norbornane skeleton with a reactive acid chloride functional group. This compound matters for its role as a key intermediate in the synthesis of complex molecules, enabling the introduction of the dimethylbicycloheptane moiety, which can impart unique steric and conformational properties. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex drug candidates, particularly those requiring rigid, lipophilic scaffolds for receptor binding.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides where the bicyclic structure contributes to biological activity and environmental stability.
• Advanced Material Precursor: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers with tailored thermal and mechanical properties.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for stereoselective synthesis, cycloaddition reactions, and the preparation of chiral ligands.
• Fragrance and Flavor Chemistry: Potential intermediate for synthesizing unique terpene-derived aroma chemicals with complex, woody olfactory notes.
• Chemical Biology Probe Development: Useful for labeling or modifying biomolecules to study protein-ligand interactions or cellular processes.

Basic Information

Product Name	3,3-Dimethylbicyclo[2.2.1]heptane-2-propionyl chloride
CAS No.	85099-15-6
Molecular Formula	C₁₂H₁₉ClO
Molecular Weight	214.73 g/mol
Synonyms	2-(3,3-Dimethylbicyclo[2.2.1]hept-2-yl)propionyl chloride; 3,3-Dimethyl-2-norbornanepropionyl chloride; Bicyclo[2.2.1]heptane-2-propionyl chloride, 3,3-dimethyl-; 3,3-Dimethylnorbornane-2-propionyl chloride; 2-(3,3-Dimethyl-2-norbornanyl)propionyl chloride; 3,3-Dimethylbicyclo[2.2.1]hept-2-ylpropionyl chloride; 2-(3,3-Dimethylbicyclo[2.2.1]heptan-2-yl)propanoyl chloride
EINECS	Contact for details

Quality Control

Our 3,3-Dimethylbicyclo[2.2.1]heptane-2-propionyl chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity assays and structural confirmation, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing specific results for purity, identity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, the container must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening and protected from moisture ingress. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.